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Title
Placental Role in Mediating Adverse Outcomes in Obstructive Sleep Apnea

Formal Study Name
Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)

Organization
Women & Infants

Research Type
Clinical

Area of Study
Sleep

Related Publications

https://www.nlm.nih.gov/medlineplus/sleepapnea.html


Eligibility Criteria

Pregnant snorers without obstructive sleep apnea, have a BMI greater than 30 kg/m2 at recruitment, older than 18 years of age, and greater than 13 completed weeks of gestation (confirmed by last menstrual period or early pregnancy dating ultrasound during qualification). Intention to reside locally and deliver at Women & Infants Hospital of Rhode Island. Ability to give informed consent.


Recruitment Status
Open

Recruitment End Date
08/30/2019

Study Start Date
06/01/2015

Description

This study is testing the hypothesis of whether continuous positive airway pressure (CPAP) therapy improves placental histopathology and secretory function. The main aims of the study are to identify shared mechanisms between obstructive sleep apnea and preeclampsia, both common highly morbid conditions.


Contact Information

tsequeira@lifespan.org