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Oncology Research

The Research Program in Women’s Oncology

The Research Program in Women’s Oncology at Women & Infants Hospital is a nationally recognized leader in gynecologic and breast cancer clinical trials.

The fundamental mission of the program is to provide patients with the latest in treatment options and access to research on prevention, screening, survivorship, and quality of life for those women affected by gynecologic or breast malignancies. This is done through several resources. First, and most important, is the program’s participation in NRG Oncology. NRG Oncology is a National Cancer Institute funded, multi-institutional, cooperative research group with a major focus on gynecologic and breast cancer treatment. Additional resources include direct interaction with the pharmaceutical industry with its access to many novel agents, such as immunotherapeutics, immune modifiers and targeted therapies, along with programs developed primarily here at Women & Infants Hospital.

An exciting development over the past several years has been the program’s participation in the phase I program of the Gynecologic Oncology Group. Phase 1 research evaluates newly developed drugs for their safety and efficacy as well as novel combinations for cancer treatment. As the only institution in Rhode Island and the surrounding communities offering this option, Women & Infants is committed to providing this level of care to its patients. Led by Dr. Cara Mathews, Women & Infants is a leader in the number of phase 1 trials offered and participants involved.

In addition to treatment trials, the Program in Women’s Oncology has gained further stature through the investigation of survivorship issues relevant to its patients. One example of this is the recently approved study led by Dr. Katina Robison through the National Patient Care Outcomes Research (PCORI) mechanism, funded by the National Institutes of Health, evaluating urinary tract health in women affected by uterine cancer. This project showcases collaboration between several of the divisions within Women & Infants Hospital as well as other institutions regionally and nationally.

Contact Information:

Program in Women's Oncology
One Blackstone Street, Providence, RI
(401) 274-1122, ext. 48181

Paul DiSilvestro, MD, Director
William Sikov, MD, Co-Director
Cara Mathews, MD, Phase 1