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Women & Infants
 
Women & Infants Center for Reproduction & Infertility
In Vitro Maturation

What is In Vitro Maturation?
In Vitro Maturation (IVM) is a process by which immature eggs are harvested from the ovaries and matured in the laboratory.

Why do eggs need to be mature?
The majority of eggs in the ovary are “immature.”  This means that they have not completely developed and cannot be fertilized.  During a normal menstrual cycle, one egg becomes mature and ovulates.

How are eggs matured during in vitro fertilization (IVF)?
During traditional IVF treatment, medication is used to encourage the production of multiple mature eggs.  These eggs are then harvested and fertilized.
With IVM, less medication is used.  Immature eggs are retrieved and are then matured in the laboratory before fertilization.  This shortens the treatment cycle and decreases the chance of side effects from the medication.

Who should consider IVM?

  • Women less than 35 years old
  • Women with polycystic ovarian syndrome (PCOS)
  • Women with a history of hyperstimulation on fertility medications
  • Women with a history of poor oocyte (egg) quality
  • Women planning to have chemotherapy

What are the benefits of IVM?

  • Avoids side effects resulting from gonadotropin stimulation
  • Reduces patient cost
  • Lessens patient discomfort
  • Simplifies treatment – fewer drugs and needles

Why should I consider having treatment at Women & Infants?
Women & Infants’ Center for Reproduction and Infertility has been designated as a Center for IVM Excellence by SAGE InVitro Fertilization, and the doctors and embryologists are highly trained in this specialized technique.  Women & Infants is currently the only training center for SAGE In Vitro Fertilization for teaching IVM to other doctors and technicians. 

What insurance do we accept?
The Center accepts most major insurance plans, including:

  • Blue Cross & Blue Shield of Rhode Island and Massachusetts
  • Harvard Pilgrim Health Care of New England
  • United Health Plan
  • Tufts Health Plan
  • CIGNA

Patients may speak with a financial and insurance coordinator to help determine their specific plan participation and eligibility.


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