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Women & Infants Center for Reproduction & Infertility
Hormone Replacement Therapy

Menopause          A Women's Guide to Menopause    

The Menopause Program at Women & Infants

What is hormone replacement therapy (HRT)?

HRT is a treatment that is often prescribed to postmenopausal women to help relieve symptoms that accompany menopause: hot flashes, night sweats, vaginal dryness, and sleeplessness.  HRT has also been prescribed to prevent some long-term health problems that can accompany menopause, such as cardiovascular disease and osteoporosis or bone loss.

Hormonal treatment may consist of estrogen alone, prescribed for women who have had a hysterectomy, or a combination of estrogen and progestin (a synthetic form of progesterone) for women who still have a uterus and are going through menopause.

In its study of estrogen plus progestin, the Women’s Health Initiative study investigated a popular brand name HRT called Prempro.  The hormones taken by the women in the study were 0.625 milligrams of conjugated equine estrogens daily) and 2.5 milligrams of  medroxyprogesterone acetate (daily.)

The WHI study found that HRT actually increases the risks of developing cardiovascular disease, blood clots, stroke,  and invasive breast cancer.  Some benefits of HRT continue to be supported by the study, including fewer cases of colorectal cancer and fewer bone fractures.

If you are taking HRT, what should you do?

This is a complex issue with individual risks and benefits.  Women who are taking HRT should talk with their physician about continuing or ending their use of HRT in a timely but not emergent fasion to see how these results apply to them personally, and what is the best course of action for them.

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The Menopause Program at Women & Infants Hospital
Appointments may be made through your own primary care provider or by calling (401) 274-1122, extension 42721.

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