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Research in the News

Research Fellow Receives Honorable Mention for Paper Submission
Postdoctoral research fellow in the Department of Obstetrics and Gynecology, Dr. Valery Danilack, received an Honorable Mention for her SPER Student Prize Paper Award submission at the Annual Meeting in June. Her paper explored best models to predict cesarean delivery after labor induction based on risk scores of 10 characteristics. Details
 
Dr. Shibin Cheng and Team Win Best Poster at American Society for Reproductive Immunology Annual Meeting

Drs. Shibin Cheng, James Padbury and Surendra Sharma won Best Poster Award at the ASRI Annual Meeting for their poster presentation on similarities in development between preeclampsia and Alzheimer's. Both diseases are thought to have a common link in protein misfolding and aggregation and process similarly. The work is part of a long-term project in the laboratory of Dr. Sharma at the Kilguss Research Institute of Women & Infants. Details

Women & Infants Team Publishes Research About Treatment for Obese Women Undergoing Cesarean Deliveries

Lindsay Maggio, MD, Melissa DaCosta, PharmD, Dwight J. Rouse, MD, and Brenna L. Hughes of Women & Infants Hospital with David P. Nicolau, PharmD at the Center for Infective Research and Development at Hartford Hospital recently published their clinical trial in Obstetrics & Gynecology. Their findings suggest that obese women undergoing cesarean delivery do not need a higher dose of antibiotics to prevent surgical site infection. Details
 
Maternal-Fetal Medicine, Obstetrics and Gynecology Doctors Publish in Obstetrics & Gynecology

A collaborative team of Women & Infants and University of Texas Medical School physicians were recently published in Obstetrics & Gynecology for their maternal-fetal medicine research regarding fetal growth restrictions and suggested management of elevated dopplers. Details                                              

 
AUGS Pelvic Floor Disorders Research Foundation Awards $25,000 Grant to Division of Urogynecology and Reconstructive Pelvic Surgery

Urogynecology fellow, Dr. Annetta Madsen, has been awarded a two-year, $25,000 grant through AUGs for her project "Improving Patient-Centered Care for Pelvic Floor Disorders through Perioperative Peer Support." Dr. Vivian Sung, director of urogynecology research, is serving as Dr. Madsen's mentor for the duration of the project. Details 

WIH Receives $5 Million Grant from NIH to Continue Work on Perinatal Biology

Women & Infants has recently received a nearly $5 million grant from the National Institutes of Health (NIH) to support an Institutional Development Award (IDeA) Center of Biomedical Research Excellence (COBRE) for Perinatal Biology. Of the more than 100 COBREs across the country, Women & Infants is the only one specifically focused on developmental research. Details  

Research About Unexpected Complications of Low Risk Pregnancies Published in AJOG
When a woman becomes pregnant or is planning a pregnancy, one of her first decisions is where she will deliver her baby. With options ranging from birthing centers to small community hospitals to regional health networks to academic medical centers, the decision can be confusing. The question, especially for a woman with a low-risk pregnancy, is "What is the likelihood that something could go wrong?" Details

Women & Infants Gynecologic Oncologist Earns Prestigious Research Funding
Dr. Katina Robinson, a gynecologic oncologist with the Program in Women's Oncology was awarded more than $2.7 million in contracted funding by the Patient-Centered Outcomes Research Institute. The study, "Cancer of the Uterus and Treatment of Stress Incontinence (CUTI)" is focused on improving the quality of life for women who undergo surgery for endometrial cancer by screening for and offering treatment of existing stress urinary incontinence at the same time as their cancer surgery. Details

Drs. Rebecca Allen and Brenna Hughes Rank Among Top Ten Percent of Peer Reviewers of Journal

Drs. Allen and Hughes are found to be most knowledgeable, dedicated and prompt as national peer reviewers of submissions to Obstetrics & Gynecology, the Official Publication of the American College of Obstetricians and Gynecologists. Details                                              

Dr. Lindsay Maggio Honored by SMFM
Research by Dr. Lindsay Maggio, a fellow in the Division of Maternal-Fetal Medicine, was selected as the nation's best fellow research paper at the Society of Maternal-Fetal Medicine's annual meeting.  The research focused on the use of prophylactic antibiotics with obese pregnant women. Details

Dr. Barry Lester Contributes to the Conversation on Epigenetics
Dr. Barry M. Lester, along with James F. Padbury, MD, chief of pediatrics at Women & Infants and the Oh–Zopfi Professor of Pediatrics and Perinatal Research at Brown University, and epigeneticist, Carmen Marsit, PhD, adjunct assistant professor of epidemiology at Brown University, have been working together researching epigenetic and environmental factors that lead to the development of many mental health disorders in children. Details

Women & Infants Oncologist Wins National Research Award
The Gynecologic Oncology Group (GOG) Foundation recently announced that Cara Mathews, MD, of the Program in Women's Oncology at Women & Infants earned its national Young Investigator Award for 2015 for her presentation, "Survival in advanced endometrial cancer: Does time to chemotherapy matter?" Details

Triple-Negative Breast Cancer Presurgery Chemotherapy Benefits
Dr. William Sikov, associate chief of clinical research with the Program in Women's Oncology at Women & Infants and associate professor of medicine at The Warren Alpert Medical School of Brown University, found that adding either carboplatin or bevacizumab to standard chemotherapy treatment before surgery helped triple-negative breast cancer patients. Details
 
Dr. Glenn Palomaki Contributes to Debate on Breast Cancer Screening
What are the risks and benefits of screening for BRCA1 and BRCA2 mutations in the general adult population? Dr. Glenn Palomaki has published an invited commentary in Genetics in Medicine on this issue. Details
 
Jesse Bender, MD, and Simulation Lab Team Awarded Grant to Expand TESTPILOT Study
A method for pre-implementation first organized prior to the opening of the Women & Infants single-family room neonatal intensive care unit (NICU), Dr. Bender and his team have been awarded a substantial grant to broaden the impact of this study on other disciplines in any hospital. Details
 
Should Pregnant Women Eat Fish? To eat fish or not to eat fish?
That is the question for pregnant and breastfeeding women. Dr. Katharine Wenstrom clarifies this complicated issue in a Viewpoint in the American Journal of Obstetrics & Gynecology. Details
 
Study examines how mothers and fathers converse with their infants
Research led by Dr. Betty Vohr has shown the importance of reading, talking and singing in infant and toddler language development, and a new study examines the role of gender in these parent-child conversations. Details
 
Obstetrician/Gynecologist at Women & Infants Hospital Publishes Book on Contraception for Medically Challenging Patients
Rebecca H. Allen, MD, MPH and assistant professor of obstetrics and gynecology at The Warren Alpert Medical School of Brown University, has published a book that offers advice on how to meet the contraceptive needs of women with chronic medical problems. In the book, Dr. Allen explains that these women need more family planning care than most so that their specific needs can be appropriately addressed ahead of delivery. Details
 
Women & Infants Researchers Examine Gynecologic Cancers and HPV Link Katina Robinson, MD, of the Program in Women's Oncology recently presented research that demonstrates a link between gynecologic cancer and human papillomavirus (HPV) infection. Details
 
Research evaluates outcomes in single family room NICU
Research led by Drs. Barry Lester and James Padbury finds that single family room NICU offers more opportunities to provide care that improves outcomes, such as increased maternal involvement and increased developmental support. Details
 
WIH Researchers Examine Role of Hormone in Patient Responses to Ovarian Cancer Treatment
Women & Infants Hospital's Program in Women's Oncology publishes work detailing improved methods of therapy to address ovarian cancer. Details
 
Women & Infants Breast Cancer Specialist Reports Advance in Treatment of Triple-Negative Breast Cancer
Medical oncologist Dr. William M. Sikov publishes national study aimed at combating aggressive form of disease. Details
 
Dr. Brenna Anderson publishes commentary in international journal
Brenna Anderson, MD, of the Division of Maternal-Fetal Medicine, has published a commentary in the current issue of BJOG: An International Journal of Obstetrics and Gynaecology, now available online. The commentary is entitled "The time has come to consider neonatal outcomes when designing embryo transfer policies." Details
 
Clinical Review Published in Journal of the American Medical Association
Many women experience mixed urinary incontinence, urine loss with laughing, coughing and sneezing (stress urinary incontinence) AND on their way to the bathroom (urge urinary incontinence). Dr. Deborah Myers has published a clinical review on on the topic in JAMA. Details                                             

Clinical Opinion Published in AJOG

A clinical opinion by Dr. Charles Rardin about the use of robotics for minimally invasive gynecologic surgery has been published in the May edition of the American Journal of Obstetrics & Gynecology. Details                                             

Clinical Review Published in Journal of the American Medical Association
Many women experience mixed urinary incontinence, urine loss with laughing, coughing and sneezing (stress urinary incontinence) AND on their way to the bathroom (urge urinary incontinence). Dr. Deborah Myers has published a clinical review on on the topic in JAMA. Details                                             

Dr. James Padbury Earns March of Dimes Prematurity Research Initiative Grant

With the help of funding from the March of Dimes, James F. Padbury, MD, is one of five scientists whose work toward discovering the causes of and reducing the rates of prematurity will be supported by March of Dimes Prematurity Research Initiative (PRI) grants in 2014. Details
 
Hypnotherapy reduces hot flashes in breast cancer patients
A team of researchers affiliated with the Program in Women's Oncology and Division of Pathology and Laboratory Medicine Women & Infants Hospital of Rhode Island recently revealed study findings indicating that hypnotherapy effectively reduces hot flashes in breast cancer survivors by 80 to 85 percent. Details
 
Maternal-Fetal Medicine Specialist Co-Authors Obstetric Care Consensus
Dr. Dwight J. Rouse has co-authored the first in a new, joint series called “Obstetric Care Consensus” that is being introduced by the American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM). This issue addresses the rapid increase in cesarean birth rates and outlines a multifaceted approach that addresses indications for primary cesarean delivery. Details
 
Dr. Brenna Anderson Contributes to Clinical Expert Series on Group A Strep Infection in Pregnancy
Brenna Anderson, MD, director of the Women’s Infectious Diseases Consultative Service at Women & Infants of Rhode Island and an associate professor of obstetrics and gynecology at The Warren Alpert Medical School of Brown University, has published an article as part of a Clinical Expert Series in the April 2014 edition of Obstetrics & Gynecology, now available online. The article, entitled “Puerperal Group A Streptococcal (GAS) Infection: Beyond Semmelweiss,” offers a description of the recommended approach to diagnosing and treating GAS in pregnant and postpartum women.
 
Higher Risks Among Perinatal Women with Bipolar Disorder
Pregnant and postpartum women with bipolar disorder more frequently have significant mental health and early mothering challenges than other perinatal women undergoing psychiatric treatment, according to a study in the Journal of Affective Disorders. The findings indicate the importance of properly identifying the disorder and developing specific treatments for women during and after pregnancy, the lead author said.  Details

Targeted way to treat ovarian cancer discovered
Researchers at Women & Infants Hospital of Rhode Island have developed a biologic drug that would prevent the production of a protein known to allow ovarian cancer cells to grow aggressively while being resistant to chemotherapy. This would improve treatment and survival rates for some women. Details

Clinical Opinion Published in American Journal of Obstetrics & Gynecology
A clinical opinion written by third year resident Maureen Hamel, MD, along with maternal-fetal medicine specialists Brenna Anderson, MD and Dwight Rouse, MD, of the Department of Obstetrics and Gynecology at Women & Infants Hospital of Rhode Island and The Warren Alpert Medical School of Brown University, has been published in the January 10, 2014 online edition of the American Journal of Obstetrics & Gynecology. Details

Study Shows that Premature Infants Benefit from Adult Talk
Research led by a team at Women & Infants Hospital of Rhode Island and The Warren Alpert Medical School of Brown University has been published in the February 10, 2014 online edition of Pediatrics, the official journal of the American Academy of Pediatrics.The research indicates that premature babies benefit from being exposed to adult talk as early as possible. Details

Researchers to Try to Determine Which Premature Infants Are at Greatest Risk for Developmental Impairment
Women & Infants has earned a five-year, $3 million grant from the National Institute of Health's National Institute of Child Health and Human Development to determine the efficacy of a neurobehavioral exam that may help to identify which infants are at greatest risk for developmental impairment.  Details
 
Cry Analyzer Seeks Clues to Baby's Health
Researchers at Brown University and Women & Infants have developed a new tool that analyzes the cries of babies, searching for clues to potential health or developmental problems. Slight variations in cries, mostly imperceptible to the human ear, can be a "window into the brain" that could allow for early intervention. Details
 
Researchers Study Women Who Choose DNA Prenatal Screening Test
Researchers at Women & Infants have received an industry grant from Natera, Inc. to determine the level of information and education needed to offer a DNA-based prenatal blood test to all pregnant women to screen for Down syndrome and similar chromosome abnormalities. Details

Intervention can prevent PPD in adolescents
By targeting the factors that may play a significant role in the development of postpartum depression (PPD) in adolescent mothers, researchers at Women & Infants Hospital of Rhode Island believe they have found a way to prevent it. Details 

Physician Earns NIH Grant
Kristen A. Matteson, MD, MPH, of the Department of Obstetrics and Gynecology, has earned a $1.6 million grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the NIH to study the effectiveness of treatment options for heavy menstrual bleeding. Details  

Women over 40 still need effective contraception
Women reaching the age of 40 tend to be less vigilant about birth control because they think the risk of pregnancy is low – or that birth control can cause health problems - but a review of the evidence by a team that includes a Women & Infants Hospital of Rhode Island physician recently underscored the need to be vigilant about contraception even in perimenopause. Details  

Abnormal Stress Response Seen in Toddlers Exposed to Meth in Womb
Some two-year-olds whose moms used methamphetamine during pregnancy may have an abnormal response to stressful situations, according to a study in the May issue of the Journal of Studies on Alcohol and Drugs. Details

Oncologist expands HPV research to anal cancer
A basic connection of statistics lead a researcher at Women & Infants Hospital of Rhode Island to question whether women should be screened for anal cancer during a regular visit to the gynecologist, and what technique is most effective. Katina Robison, MD, a gynecologic oncologist with the Program in Women's Oncology, has launched recruitment for her new study, "Anal cytology and HPV genotyping in women with lower genital tract neoplasia." Details  

Research Shows Connection Between Tubal Ligation, Cervical Cancer
Women who have a tubal ligation – the surgical tying or severing of fallopian tubes to prohibit pregnancy – have less frequent Pap smears, which puts them at an increased risk for cervical cancer, according to research recently released by a team that included Cara A. Mathews, MD, a gynecologic oncologist at the Program in Women's Oncology at Women & Infants Hospital of Rhode Island. Details  

Researchers Study Cry Acoustics of Infants to Determine Risk for Autism
Understanding the importance of early diagnosis, researchers at Women & Infants' Brown Center for the Study of Children at Risk in collaboration with researchers at University of Pittsburgh have been studying the cry acoustics of six-month-old infants.Their research has recently been published in Autism Research. Details 

Researchers study protein level-ovarian cancer link
Researchers with the Center for Biomarkers and Emerging Technologies (CBET) at Women & Infants Hospital are investigating whether the level of a specific blood protein fluctuates during a woman's normal menstrual cycle to help them furher diagnose a mass as ovarian or endometrial cancer. Details  

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