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Baby Aspirin Patient Information - IVF Guide

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Background
Aspirin (Acetylsalicylic acid) is among the most commonly used drugs. Low dose (baby aspirin) is being taken more and more to reduce such things as heart attacks and strokes. There is increasing data to suggest that taking a single baby aspirin each day can improve pregnancy outcomes with fertility treatments such as In Vitro Fertilization.

Why would a baby aspirin improve pregnancy rates?

There are several theories:

  • Aspirin has a positive affect on the body’s immune system and the associated antibodies which may interfere with the embryo’s ability to attach to the lining of the uterus.
  • Baby aspirin may help improve blood supply to various organs. This might help to:
    • improve the quality or number of eggs produced by the ovaries
    • improve the lining of the uterus
    • and/or help keep the blood vessels of the placenta open.

Should I take a baby aspirin?
We suggest that some of our patients take baby aspirin unless it is medically contraindicated for them. Please check with your doctor before taking this medication.

Dose and instructions
How much should I take?

  • Take one baby aspirin per day. This may say “low-dose” or “baby” aspirin on the label and should contain between 78-82mg of aspirin per tablet.
  • Do not take a full dose aspirin or a nonsteroidal medication such as Ibuprofen instead.
  • More is not better. Taking more than one baby aspirin a day may decrease your fertility and be dangerous to your health.
  • If you have any questions about the dose of the aspirin you have selected, please ask your pharmacist or one of our staff.

We suggest that you start taking a baby aspirin now (as opposed to starting only when on fertility drugs) to achieve the potential maximum benefits as well as to see if you have any side affects prior to being in the middle of fertility treatment.

Risks
Taking one low-dose baby aspirin a day is very safe and well tolerated. It is not common to have a true allergic reaction to aspirin.

When is it NOT safe to take a baby aspirin?

Do not a take a baby aspirin if you have any history of the following:

  • Significant bronchospasm or rhinitis
  • Nasal polyps
  • Asthma
  • Allergic skin reactions
  • Bleeding disorders
  • Allergies
  • Sensitivity to aspirin or Ibuprofen
  • G6PD

Are there any other concerns when taking baby aspirin?

  • Your blood may be slightly thinner. We suggest that you keep pressure on your blood draw sites for longer than you usually would.
  • Low dose aspirin is safe in early pregnancy. Your doctor will tell you when to stop the aspirin. We suggest that you do not continue taking aspirin after the first trimester unless you are taking it for medical reasons.
  • Please limit your alcohol intake while taking aspirin. It may cause problems with your stomach and intestine.
  • If you get an upset stomach or have concerns about ulcers, coated baby aspirin is available and should be as effective.
  • While you are on the baby aspirin, we suggest that you limit the following: curry powder, gherkins, licorice, paprika, prunes, raisins, tea and significant use of non-absorbable antacids such as Maalox or Rolaids.

If you have any questions, please do not hesitate to ask your doctor.

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